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help needed

Annie Cheng anniec at postgres.berkeley.edu
Thu Apr 2 14:48:39 EST 1998

Dear Professors and Graduate Students,

We are graduate students in biological and computer sciences at
University of California, Berkeley.  We are currently working on a
research project which aims at optimizing the current sequence search
tools that are used in biological sciences. Biologists need these tools
to find matched sequences, homologs, motifs etc from the sequence
The sizes of those sequence libraries grow every day, especially with
the progressing of genome projects. An efficient and accurate search
method will greatly help the biologists' researches.  Also it will
benefit the biologists if they know which search tool is most
effiecient for which kind of search work.

For this purpose, we are tring to come out with a justified benchmark to

test the efficiency and accuracy of current sequence search tools and
our new search tool.  We need your professional biological
knowledge and experience.  We will be greatly appreciated if you can
help us by answering the following questions.

Upon your experience with any biological sequence search tool:
  1. Please give one or more query sequence(s) you worked with before.
  2. Please give the name of search tool(s) you used.
  3. Please give the database(s) you searched.
  4. Please list all search results for each query sequence that you
     believe are useful, important or related to your research. The
     could come from many searches or from several different search
  5. Please give the access number for each result sequence.

Please reply this mail as soon as possible to
anniec at postgres.berkeley.edu.
If you have any questions, please feel free to contact us.  Thank you
reading this mail and your help will definitely make a difference for
our research.


Annie Cheng and Guochun Liao

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