Mark:
{*} I have a non-proline cis-peptide bond in a structure i've recently
{*} determined, and would like to know how many other's there are.
{*}
{*} Has anyone compiled a list of protein structures containing such bonds?
{*} Or have any idea how i could go about compiling such a list? I've been
{*} unable to design a database search for these bond types, without calling
{*} up all the cis-prolines.
Take a look at the work of Stewart & colleagues from Georgia:
Stewart DE; Sarkar A; Wampler JE.
Occurrence and role of cis peptide bonds in protein structures.
Journal of Molecular Biology, 1990 Jul 5, 214(1):253-60.
Some interesting ones that come to my mind are:
RNAse T1
Beta lactamase
Carbonic anhydrase
Dihydrofolate Reductase
Cheers
-raman
___________________________________________________________________
C.S.Raman Tel: (714) 824-4322
University of California Fax: (714) 824-3280
Dept. MB & B, SH530 email: craman at uci.edu
3205 Bio Sci II
Irvine, CA 92697-3900
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