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POSTDOCTORAL POSITIONS IN PROTEIN CRYSTALLOGRAPHY

Raymond C. Stevens stevens at ADRENALINE.BERKELEY.EDU
Mon Oct 26 18:49:11 EST 1998


POSTDOCTORAL POSITIONS IN PROTEIN CRYSTALLOGRAPHY AT 
THE SCRIPPS RESEARCH INSTITUTE/ NOVARTIS INSTITUTE FOR FUNCTIONAL GENOMICS

  The Stevens Laboratory will be relocating to The Scripps Research Institute 
next June, and several postdoctoral research positions are available.  In addition to 
having a well equipped and well funded state-of-the-art laboratory, the group will 
have unique resources including (1) automated protein purification, (2) automated 
crystallization, and (3) automated crystal screening equipment.  The crystallization & 
analysis robot (T-2000) can handle approximately 11,000 trials per day (screening 
robot can handle approximately 25,000 trials per day).  In addition, a dedicated 
synchrotron beamline has been obtained for high throughput structure determinations. 
The approach of the research group is that research time will be dedicated 
to solving and studying a large number of selected protein structures and protein structure 
complexes for better insight into the systems.  The above resources will allow for 
very high throughput data collection and structure determination on a variety of 
projects.  

  The primary focus of research is structural neurobiology (axon guidance, G 
protein-coupled receptors, neuroenzymes, neurotoxins) and biocatalysis/evolution 
(directed evolution of enzymes and catalytic antibodies).  Please consult our 
homepage at http://www.cchem.berkeley.edu/~rasgrp for details on many of the 
current projects.

  Postdoctoral positions are available at both The Scripps Research Institute and the 
newly formed Novartis Institute for Functional Genomics which are closely coupled 
together. The Novartis Institute will house a consortium of researchers using robotics 
systems for high throughput protein evolution, combi-chem, drug screening, protein 
expression/purification, crystallization/analysis and bioinformatics.  Candidates 
should have research experience in either X-ray crystallography, molecular biology or 
protein biochemistry.   Appointees will receive competitive salaries and employee 
benefits including incoming travel and moving expenses.

Applicants should send a CV, list of publications, and the names, addresses and 
telephone numbers of three references to the below address, where we will be until 
June 1999. 

Professor Raymond Stevens
Department of Chemistry
University of California
Berkeley, CA 94720




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