This is the information file for MATRIX: a new Gel Imaging software package for Microsoft Windows developed by QUANTAVISION CANADA. GENERAL INFORMATION: The MATRIX evaluation program is called MATRIX-DEMO.EXE and can be downloaded from the IUBIO FTP site at Indiana University . It is a Windows self-extracting program that leads you through the installation process. You can also go to QuantVision's HomePage at for additional information, screen shots, and up-to-date links for downloads. MATRIX DESCRIPTION: MATRIX contains tools for image enhancement, molecular weight determination, and quantitation. For image enhancement, MATRIX provides basic tools to crop, rotate (as little as 1° increments), invert, magnify, sharpen and soften an image. Images can also be adjusted using brightness/contrast controls or by a histogram for optimal conditions. MATRIX automatically detects bands for lane analysis and contains an internal listing of popular DNA/protein markers for molecular weight calibration and determination. Additional markers can be added and existing ones can be modified. MATRIX provides two methods of DNA/protein band determination. (1) A qualitative approach for quickly assessing relative intensities between bands on the gel image and (2) a quantitative approach involving lane analysis. MATRIX contains a chart mode to plot image data and analysis peaks from lane analysis. MATRIX can change peak sensitivity, add/remove peaks, adjust peak limits, and provide different methods of background subtraction. Multiple lanes can be plotted for comparison, printed, and exported to other applications. MATRIX provides a special spreadsheet for quantitative band analysis. The spreadsheet can automatically calculate the quantity contained in each band. LIMITATIONS OF EVALUATION EDITION: Anyone distributing the MATRIX Evaluation program for any kind of remuneration must first contact QuantaVision. You are, however, encouraged to pass a copy of the MATRIX program (Self-extracting executable file) to other interested parties for evaluation. The following features are not available in "evaluation mode" until an authorization key is added to the system: 1. Saving experiments and data 2. Printing 3. Copying to other applications 4. Adding more than 2 lanes for analysis Authorization keys can be purchased directly from QuantaVision Canada or through a licensed MATRIX distributor. NOTE: Switching from Image Analysis to Chart Analysis automatically recalculates lane data. Thus any changes previously made to the chart and spreadsheet will be removed (chart and spreadsheet data are normally saved prior to returning to Image Analysis). MATRIX (tm) Copyright (c) QuantaVision CANADA All rights reserved