profin11.readme PromFind (promoter find) is a MS-DOS program to identify the promoter region in a vertebrate DNA sequence. The algorithm operates by scoring the sequence using a differential hexamer measure. The program accepts sequence files in GenBank, EMBL, Fasta and plain format. It requires a 386 microprocessor or higher. PromFind is designed to operate in tandem with two other programs, SorFind (that predicts coding exons in vertebrate DNA) and RepFind (that identifies common repetitive elements). All three programs create a feature table, or if one is already present modifies the feature table to include the predictions. If you use this program in your research, please cite the following: Hutchinson, G.B., The Prediction of Vertebrate Promoter Regions Using Differential Hexamer Frequency Analysis. Comp. Appl. Biosci. (1996) In Press. The program is packaged as a self-executing binary file that contains the following files: promfind.exe - the MS-DOS executable promD1.hex and promD2.hex - required data files of hexamer frequency promfind.doc - a manual in Microsoft Word format promfind.txt - the same manual as a text file (not as pretty) The program is provided free of charge, and thus there is no warranty, expressed or implied. Gordon B. Hutchinson (hutch@netshop.bc.ca) July 9, 1996