profin11.readme

PromFind (promoter find) is a MS-DOS program to identify the promoter 
region in a vertebrate DNA sequence. The algorithm operates by scoring 
the sequence using a differential hexamer measure.

The program accepts sequence files in GenBank, EMBL, Fasta and plain 
format. It requires a 386 microprocessor or higher. PromFind is designed 
to operate in tandem with two other programs, SorFind (that predicts 
coding exons in vertebrate DNA) and RepFind (that identifies common 
repetitive elements). All three programs create a feature table, or if 
one is already present modifies the feature table to include the 
predictions. 

If you use this program in your research, please cite the following:

Hutchinson, G.B., The Prediction of Vertebrate Promoter Regions Using
Differential Hexamer Frequency Analysis. Comp. Appl. Biosci. (1996) 
In Press.

The program is packaged as a self-executing binary file that contains 
the following files:

promfind.exe				- the MS-DOS executable
promD1.hex and promD2.hex	- required data files of hexamer frequency
promfind.doc				- a manual in Microsoft Word format
promfind.txt				- the same manual as a text file (not as 
pretty)

The program is provided free of charge, and thus there is no warranty,
expressed or implied.

Gordon B. Hutchinson (hutch@netshop.bc.ca)
July 9, 1996