loopDloop in Java an application for visualizing RNA secondary structure version 2.07b, August 1997 loopDloop is a tool for drawing RNA secondary structures in molecular biology. It reads files of biosequence data with base pairing information, and displays graphic views of the secondary structure. Options allow you to modify, adorn and edit the structure. Standard application functions to save, print, edit and manage preferences are included. This program will not produce base pairings needed for secondary structure. This software is available at ftp://iubio.bio.indiana.edu/molbio/loopdloop/java/ http://iubio.bio.indiana.edu/soft/molbio/loopdloop/java/ LoopDloop is now written as a Java application. This means that it will run on most personal computers and workstations as a standard program or application. The current release is lacking some features of prior Macintosh releases. Please read the installation instructions included in loopdloop-doc.html with the software. The current release takes some work to install, including perhaps a java runtime system for your computer. Java versions of other molecular biology applications built with the same framework are or will soon be updated : SeqPup - a biological sequence editor and analysis program Phylodendron - a phylogenetic tree drawing application FlyNapp - a FlyBase Drosophila database network application The Java language has several important aspects and some current drawbacks for biocomputing software. Please try some of these programs and let me know if you think these are going in the right direction. Developers will find the source code all these applications in the iubio:/molbio/java/source folders. The four current applications share about 60% code. This framework may make a useful basis for other biocomputing applications.