About DNA Runs

DNA Runs was a Macintosh program for performing a significance test of 
the 
number of runs in DNA sequence polymorphism and divergence data.  A 
complete description of the test is in:

McDonald, J.H. 1996. Detecting non-neutral heterogeneity across a region 

of DNA sequence in the ratio of polymorphism to divergence. Molecular 
Biology and Evolution 13:253-260.

The runs test is now included in the program DNA Slider, along with other 
tests that are more powerful than the runs test for most patterns of 
heterogeneity in the polymorphism to divergence ratio. DNA Slider is 
available from  ftp://iubio.bio.indiana.edu/molbio/mac.

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John H. McDonald
Department of Biological Sciences
University of Delaware
Newark, Delaware  19716

mcdonald@udel.edu